What does «síndrome mielodisplásico» mean in Spanish?
- Myelodysplastic syndromes (MDS, formerly known as "preleukemia") are a diverse set of hematologic conditions distinguished by decreased production of some or all of the three types of blood cells: erythrocytes, leukocytes, and platelets. Although not a true malignancy, MDS is nevertheless classified within the hematologic malignancies because of the risk of transformation to acute myeloid leukemia. Many disorders can cause low production of a single type of blood cell. Aplastic anemia, for example, disrupts red blood cell production, and most other hematologic diseases are selective. MDS is an error that affects all hemapoietic stem cells. MDS is a clonal disease, arising from an error in the DNA of a single cell, an error that then spreads. The error, in the early stages of the disease, accelerates blood cell apoptosis. If it develops into leukemia, an additional mutation occurs.